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Tuesday, 27 December 2011
Genetics Faculty Candidate Seminar, Giovanni Bosco, Associate Professor of Molecular and Cellular Biology, University of Arizona
Monday, 26 December 2011
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Sunday, 25 December 2011
UK News: Charity hails East Africa appeal
Dec 26 2011
Save the Children said its East Africa emergency appeal has become the most successful in the charity's history after Britons donated more than ?7 million in six months.
The appeal, which was launched in July, has surpassed the previous record of ?6.8 million raised for Asian tsunami victims.
Save the Children's chief executive Justin Forsyth said the money was spent on providing food, clean water and healthcare to 1.7 million children affected by the drought in East Africa.
"Even when times are tough at home, this shows that British people care deeply about the world's most vulnerable children," Mr Forsyth said.
"They know that their help - however small - can be the difference between life and death for children facing unimaginable suffering."
One such child is Umi, a baby girl found by Save the Children outreach staff in a remote village in rural Kenya. Mr Forsyth said Umi had life-threatening malnutrition but made a full recovery after the charity intervened.
But he said the scale of the food crisis was enormous and thousands of other children, particularly in Somalia, urgently needed help.
An estimated 250,000 people are in urgent need of assistance in Somalia, he said, just days after International Development Secretary Andrew Mitchell announced Britain was providing more than 9,000 tonnes of food supplies and medicines to drought-ravaged regions in the Horn of Africa.
Mr Mitchell told BBC Radio 4's Today programme that Somalia was a direct threat to the UK's security because it was one of the "most dysfunctional countries in the world". He said aid made "the difference between life and death" as millions across the region "face a fight for life".
The Government will host a conference on Somalia in London on February 23, Prime Minister David Cameron announced last month. Mr Cameron said Somalia was a failed state during a speech at the Lord Mayor's banquet on November 14.
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Breast Cancer Patients Face More Imaging Tests Today - iVillage
FRIDAY, Dec. 23 (HealthDay News) -- Women with breast cancer undergo many more imaging tests between diagnosis and surgery than they did in the early 1990s, a new study finds.
The tests -- breast ultrasounds, MRIs and mammograms -- help doctors determine the best course of treatment, but add to the hassles and expense of care, the study says.
"The burden to the patient is increasing substantially," said study leader Dr. Richard Bleicher, an associate professor of surgical oncology at Fox Chase Cancer Center in Philadelphia. For older patients, especially, coordination of care is needed, he said.
Bleicher, a breast surgeon, evaluated data on more than 67,000 women in the United States diagnosed with breast cancer from 1992 to 2005. His intent was to clock the time and inconvenience involved in multiple imaging appointments.
In 1992, he found that 1 in 20, or under 5 percent of patients, had imaging twice or more during the preoperative period of about 37 days. By 2005, 1 in 5 patients, or nearly 20 percent, had two or more imaging sessions.
"Patients are having a lot more imaging done overall," he said. "I can't tell you whether the imaging was appropriate or not appropriate."
The percentage of patients who had more than one type of imaging on a given day increased more than six-fold, from about 4 percent in 1992 to just over 27 percent in 2005, the study found.
A subgroup of 20 patients had five or more mammogram visits during the pre-op period, he found.
For the study, the researchers used Medicare claims linked to the U.S. National Cancer Institute's Surveillance Epidemiology End Results data for women with breast cancer. They zeroed in on about 67,750 women over age 65 who had invasive cancer that hadn't spread and who were scheduled for surgery.
Bleicher presented the findings earlier this month at the San Antonio Breast Cancer Symposium. He urged his colleagues to consider ways of streamlining the testing, with an eye to improving treatment without raising costs.
The increase in imaging tests does not surprise Dr. Carol Lee, head of the communications committee for the American College of Radiology Breast Imaging Commission.
"Practices have changed," she said. "Standards of care have changed." Since 1992, imaging technology has advanced greatly, she said, noting there are more, and better, options.
One limitation of the study, she said, is that the outcomes are not addressed. "This is not telling the whole story," she said. "What gets lost in the numbers is, what are the possible benefits of this additional imaging?"
"Yes, we are doing more tests," she said. "But we are not doing tests for the sake of doing tests."
Some states have laws that address self-referral, said Shawn Farley, spokesperson for the American College of Radiology. The specifics of the laws vary.
Lee agreed with Bleicher that doctors should strive for better coordination of imaging tests.
If your doctor orders imaging, Bleicher recommends asking why it's needed. You might also ask if the doctor expects more imaging will be needed and if so, whether it's possible to schedule tests together, he said.
The study was supported by the U.S. Public Health Service, the American Cancer Society, the Commonwealth of Pennsylvania and private donors.
Research presented at meetings should be considered preliminary until published in a peer-reviewed medical journal.
More information
For more on breast cancer imaging, see the American College of Radiology patient information page.
Source: http://www.ivillage.com/breast-cancer-patients-face-more-imaging-tests-today/4-a-413524
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FCC approves AT&T's $1.9b purchase of Qualcomm's 700MHz spectrum (update)
For the FCC's part, it has approved the deal with only a few stipulations: AT&T will be required to satisfy interference requirements and must offer data roaming to its competitors on the spectrum. That's not to suggest everyone's pleased, however. Rural cellular providers asked that, as part of the deal, AT&T must ensure that its LTE network is interoperable with the bands used by smaller networks. Sadly, the FCC has denied this request, ostensibly limiting the little guy from receiving Ma Bell's hand-me-downs.
Update: AT&T has gone ahead and released a wee bit of celebratory PR, which we're including after the break. Most importantly, it expects to wrap up the finer details in the next few days.
Continue reading FCC approves AT&T's $1.9b purchase of Qualcomm's 700MHz spectrum (update)
FCC approves AT&T's $1.9b purchase of Qualcomm's 700MHz spectrum (update) originally appeared on Engadget on Thu, 22 Dec 2011 21:20:00 EDT. Please see our terms for use of feeds.
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Three U.S. citizens killed in Mexico attacks (Reuters)
MEXICO CITY (Reuters) ? Three U.S. citizens were among those killed when gunmen attacked buses in the eastern Mexican state of Veracruz, said a U.S. State Department official said on Saturday.
The three were traveling for the holidays when they and several other passengers on the bus were killed by gunmen on Thursday, according to the U.S. official and local media.
The incident was one of several that day in which gunmen attacked busses in the eastern state, a major oil export hub that has lately become a flashpoint for drug gang violence.
On Friday, the tortured bodies of 10 people were found in northern Veracruz, local media reported, as attacks in the region intensify between the Zetas gang and Gulf drug cartels.
In September, 35 bodies were dumped along a downtown highway in the Veracruz city of Boca del Rio.
More than 45,000 people have been killed in cartel-related violence since President Felipe Calderon took office in December 2006.
(Reporting by Patrick Rucker)
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Saturday, 24 December 2011
Breast Cancer Patients Face More Imaging Tests Today (HealthDay)
FRIDAY, Dec. 23 (HealthDay News) -- Women with breast cancer undergo many more imaging tests between diagnosis and surgery than they did in the early 1990s, a new study finds.
The tests -- breast ultrasounds, MRIs and mammograms -- help doctors determine the best course of treatment, but add to the hassles and expense of care, the study says.
"The burden to the patient is increasing substantially," said study leader Dr. Richard Bleicher, an associate professor of surgical oncology at Fox Chase Cancer Center in Philadelphia. For older patients, especially, coordination of care is needed, he said.
Bleicher, a breast surgeon, evaluated data on more than 67,000 women in the United States diagnosed with breast cancer from 1992 to 2005. His intent was to clock the time and inconvenience involved in multiple imaging appointments.
In 1992, he found that 1 in 20, or under 5 percent of patients, had imaging twice or more during the preoperative period of about 37 days. By 2005, 1 in 5 patients, or nearly 20 percent, had two or more imaging sessions.
"Patients are having a lot more imaging done overall," he said. "I can't tell you whether the imaging was appropriate or not appropriate."
The percentage of patients who had more than one type of imaging on a given day increased more than six-fold, from about 4 percent in 1992 to just over 27 percent in 2005, the study found.
A subgroup of 20 patients had five or more mammogram visits during the pre-op period, he found.
For the study, the researchers used Medicare claims linked to the U.S. National Cancer Institute's Surveillance Epidemiology End Results data for women with breast cancer. They zeroed in on about 67,750 women over age 65 who had invasive cancer that hadn't spread and who were scheduled for surgery.
Bleicher presented the findings earlier this month at the San Antonio Breast Cancer Symposium. He urged his colleagues to consider ways of streamlining the testing, with an eye to improving treatment without raising costs.
The increase in imaging tests does not surprise Dr. Carol Lee, head of the communications committee for the American College of Radiology Breast Imaging Commission.
"Practices have changed," she said. "Standards of care have changed." Since 1992, imaging technology has advanced greatly, she said, noting there are more, and better, options.
One limitation of the study, she said, is that the outcomes are not addressed. "This is not telling the whole story," she said. "What gets lost in the numbers is, what are the possible benefits of this additional imaging?"
"Yes, we are doing more tests," she said. "But we are not doing tests for the sake of doing tests."
Some states have laws that address self-referral, said Shawn Farley, spokesperson for the American College of Radiology. The specifics of the laws vary.
Lee agreed with Bleicher that doctors should strive for better coordination of imaging tests.
If your doctor orders imaging, Bleicher recommends asking why it's needed. You might also ask if the doctor expects more imaging will be needed and if so, whether it's possible to schedule tests together, he said.
The study was supported by the U.S. Public Health Service, the American Cancer Society, the Commonwealth of Pennsylvania and private donors.
Research presented at meetings should be considered preliminary until published in a peer-reviewed medical journal.
More information
For more on breast cancer imaging, see the American College of Radiology patient information page.
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Wave of Bomb Attacks Kill at Least 60 in Baghdad Following Withdrawal of US Troops
Another Obama success story?
At least 60 people were killed today in 14 bomb attacks in Baghdad following the withdrawal of US troops this week.
Here?s amazing raw footage of one of the major explosions today.
A wave of at least 14 bombings ripped across Baghdad Thursday morning, killing at least 60 people in the worst violence in Iraq for months. The apparently coordinated attacks struck days after the last American forces left the country and in the midst of a major government crisis between Shiite and Sunni politicians that has sent sectarian tensions soaring.
The bombings may be linked more to the U.S. withdrawal than the political crisis, but all together, the developments heighten fears of a new round of Shiite-Sunni sectarian bloodshed like the one a few years back that pushed Iraq to the brink of civil war.
There was no immediate claim of responsibility. But the bombings bore all the hallmarks of al Qaeda?s Sunni insurgents. Most appeared to hit Shiite neighborhoods, although some Sunni areas were also targeted. In all, 11 neighborhoods were hit by either car bombs, roadside blasts or sticky bombs attached to cars. There was at least one suicide bombing and the blasts went off over several hours.
Loading the player ...
Source: http://www.liveleak.com/view?i=6c8_1324586030
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Viagra against heart failure: Researchers at the RUB and from Rochester throw light on the mechanism
[ | E-mail |
Contact: Professor Dr. Wolfgang Linke
wolfgang.linke@rub.de
49-234-322-9101
Ruhr-University Bochum
Circulation: active ingredient sildenafil makes stiffened cardiac walls elastic again
How sildenafil, the active ingredient in Viagra, can alleviate heart problems is reported by Bochum's researchers in cooperation with colleagues from the Mayo Clinic in Rochester (Minnesota) in the journal Circulation. They studied dogs with diastolic heart failure, a condition in which the heart chamber does not sufficiently fill with blood. The scientists showed that sildenafil makes stiffened cardiac walls more elastic again. The drug activates an enzyme that causes the giant protein titin in the myocardial cells to relax. "We have developed a therapy in an animal model that, for the first time, also raises hopes for the successful treatment of patients" says Prof. Dr. Wolfgang Linke of the RUB Institute of Physiology.
"Rubber band proteins" can be influenced
Sildenafil inhibits a specific enzyme (phosphodiesterase 5 A), which causes the increased formation of a messenger substance (cGMP). The messenger substance activates the enzyme protein kinase G, which attaches phosphate groups to certain proteins. This so-called phosphorylation causes blood vessels to relax, which was why the "potency pill" Viagra originally came onto the market. The Bochum and Rochester researchers found that the cardiac muscle protein titin is also phosphorylated through the same mechanism. "The titin molecules are similar to rubber bands" explains the Bochum physiologist. "They contribute decisively to the stiffness of the cardiac walls." The activity of the protein kinase G causes titin to relax. This makes the cardiac walls more elastic. The effect occurs within minutes of administering the drug.
Heart failure drugs currently not sufficient
"Of all the patients aged over 60 who are in hospital because of a weak heart, half suffer from diastolic heart failure" explains Linke. "Although we know that the decreased distensibility of the cardiac walls is the cause, the disease cannot be treated properly with today's medicines." In the so-called "Relax" study of the Heart Failure Network, the efficacy of sildenafil in people is already being tested. "If, for the first time, the drug is found to have a positive effect on heart failure, we would already have a molecular mechanism on hand to explain the effect" says Linke.
###
Bibliographic record
K. Bishu, N. Hamdani, S.F. Mohammed, M. Kruger, T. Ohtani, O. Ogut, F.V. Brozovich, J.C. Burnett, W.A. Linke, M.M. Redfield (2011): Sildenafil and B-type natriuretic peptide acutely phosphorylate titin and improve diastolic distensibility in vivo, Circulation, doi: 10.1161/CIRCULATIONAHA.111.048520
Figure online
A figure related to this press release can be found at http://aktuell.ruhr-uni-bochum.de/pm2011/pm00423.html.en
Further information
Prof. Dr. Wolfgang Linke, Department of Cardiovascular Physiology, Institute of Physiology, Medical Faculty of the Ruhr-Universitt, 44780 Bochum, Tel.: +49/234/32-29101 wolfgang.linke@rub.de
Cardiovascular physiology at the RUB
http://www.py.ruhr-uni-bochum.de/kardp/Index.html
"Relax" study
https://www.hfnetwork.org/hf-trials/relax-trial/
?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
[ | E-mail |
Contact: Professor Dr. Wolfgang Linke
wolfgang.linke@rub.de
49-234-322-9101
Ruhr-University Bochum
Circulation: active ingredient sildenafil makes stiffened cardiac walls elastic again
How sildenafil, the active ingredient in Viagra, can alleviate heart problems is reported by Bochum's researchers in cooperation with colleagues from the Mayo Clinic in Rochester (Minnesota) in the journal Circulation. They studied dogs with diastolic heart failure, a condition in which the heart chamber does not sufficiently fill with blood. The scientists showed that sildenafil makes stiffened cardiac walls more elastic again. The drug activates an enzyme that causes the giant protein titin in the myocardial cells to relax. "We have developed a therapy in an animal model that, for the first time, also raises hopes for the successful treatment of patients" says Prof. Dr. Wolfgang Linke of the RUB Institute of Physiology.
"Rubber band proteins" can be influenced
Sildenafil inhibits a specific enzyme (phosphodiesterase 5 A), which causes the increased formation of a messenger substance (cGMP). The messenger substance activates the enzyme protein kinase G, which attaches phosphate groups to certain proteins. This so-called phosphorylation causes blood vessels to relax, which was why the "potency pill" Viagra originally came onto the market. The Bochum and Rochester researchers found that the cardiac muscle protein titin is also phosphorylated through the same mechanism. "The titin molecules are similar to rubber bands" explains the Bochum physiologist. "They contribute decisively to the stiffness of the cardiac walls." The activity of the protein kinase G causes titin to relax. This makes the cardiac walls more elastic. The effect occurs within minutes of administering the drug.
Heart failure drugs currently not sufficient
"Of all the patients aged over 60 who are in hospital because of a weak heart, half suffer from diastolic heart failure" explains Linke. "Although we know that the decreased distensibility of the cardiac walls is the cause, the disease cannot be treated properly with today's medicines." In the so-called "Relax" study of the Heart Failure Network, the efficacy of sildenafil in people is already being tested. "If, for the first time, the drug is found to have a positive effect on heart failure, we would already have a molecular mechanism on hand to explain the effect" says Linke.
###
Bibliographic record
K. Bishu, N. Hamdani, S.F. Mohammed, M. Kruger, T. Ohtani, O. Ogut, F.V. Brozovich, J.C. Burnett, W.A. Linke, M.M. Redfield (2011): Sildenafil and B-type natriuretic peptide acutely phosphorylate titin and improve diastolic distensibility in vivo, Circulation, doi: 10.1161/CIRCULATIONAHA.111.048520
Figure online
A figure related to this press release can be found at http://aktuell.ruhr-uni-bochum.de/pm2011/pm00423.html.en
Further information
Prof. Dr. Wolfgang Linke, Department of Cardiovascular Physiology, Institute of Physiology, Medical Faculty of the Ruhr-Universitt, 44780 Bochum, Tel.: +49/234/32-29101 wolfgang.linke@rub.de
Cardiovascular physiology at the RUB
http://www.py.ruhr-uni-bochum.de/kardp/Index.html
"Relax" study
https://www.hfnetwork.org/hf-trials/relax-trial/
?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Source: http://www.eurekalert.org/pub_releases/2011-12/rb-vah122311.php
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Friday, 23 December 2011
Italian Olympic official predicts Canada will win 16 medals at London 2012
Canada will bring home 16 medals from the London Olympics and finish 18th in the medal standings, according to an Italian sports official who projects Games results.
Luciano Barra has Canadians winning five gold, two silver and nine bronze in his medal projections based on recent world championships.
More related to this story
?Canada in London will surely do very well because your program 'Own the Podium' is one of the best in the world,? Barra said in an e-mail to The Canadian Press. ?Still you have to remember that the Summer Games are not like the Winter!?
Still 16 medals would be two less than Canada collected in 2008 in Beijing. The Canadian team won three gold, nine silver and six bronze to finish 19th in the medal standings in China.
Barra, a former senior member of the Italian Olympic Committee, has Canada sandwiched between Hungary in 17th and the Netherlands in 19th in his projected London medal standings.
Barra has China topping the overall and gold medal count with 103 medals ? 43 gold, 31 silver and 29 bronze.
He predicts the U.S. will finish second with 82 medals ? 35 gold, 19 silver and 28 bronze. He has Russia third with 76 overall ? 30, 22 and 24.
Canada won 26 medals at the 2010 Winter Games in Vancouver ? 14 gold, seven silver and five bronze ? to finish third in total medals behind the No. 1 Americans (37) and Germany (30).
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Thursday, 22 December 2011
Carolalong and Golf Cart Parade Info
?Blogger has gone crazy.
I posted it a couple of times and I guess that confused the software.
Carolalong & Decorated Golf Cart Parade.
Break out your strings of lights,
?hang some tinsel off your missile toes..
I never even knew missiles had toes!
The house and RV?decorations will be judged 17 - 24.
? Prize for most unique beautiful home or?RV
is a dinner with Robert & Lucie!!!
?Golf cart prize is a surprise!
?(Guess that means they just don't know yet what it will be)
? Both awarded on the 24th at Flip Flopz
after parade and carolalong.?
? For the carolalong (I've been spelling it WRONG AllAlong
on every poster and blog entry!)
Meet at paved area by the pavilion and form a parade.?
?The parade will stop?at any?home who would like a carol.
(Let Karen #434?know if you want us to stop.)
?After visits & the parade libations at Flip Flopz & more singing! Christmas Cheer!!!
Source: http://sandpiperpaper.blogspot.com/2011/12/carolalong-and-golf-cart-parade-info.html
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Saturday, 22 October 2011
Asia's growth to slow, no China crash seen: Reuters poll (Reuters)
SINGAPORE (Reuters) ? China's economic growth will probably cool next year to the lowest annual rate in a decade, setting the pace for an Asia-wide slowdown as global demand fades, a Reuters poll released on Thursday showed.
But economists saw little risk of a severe slump. The slowdown should be modest and Asia's policymakers have room to ramp up government spending or lower official interest rates in case the outlook worsens.
Although China's 2012 growth will probably dip below 9 percent, none of the 30 economists surveyed thought it would breach the 8 percent line seen as the minimum for assuring sufficient job creation to keep up with urban migration.
"Contrary to what appears to be the dominant view among investors, we don't see recession anywhere in Asia," Deutsche Bank's Asia economist Michael Spencer said.
"Asia is heading into a period of six to nine months of below average growth, reflecting mostly the deceleration of activity in the advanced economies," he said.
Weak growth in the United States and Europe is already crimping exports across Asia, and economists have penciled in a sharper slowdown in the coming quarters.
Slower growth should bring inflation relief. The consensus view among economists now shows India as the only country in the polling region likely to increase interest rates in 2011.
In the previous quarterly poll, conducted in July, economists had predicted more rate rises by the end of 2011 in India, Indonesia, Thailand, Taiwan, Malaysia, New Zealand, Australia and South Korea.
The Reserve Bank of India will probably raise rates at its meeting next week, but that is widely expected to be the last move in its aggressive tightening cycle. Economists expect two quarter-point cuts in 2012.
Indonesia already lowered rates in a surprise move on October 11, and the poll shows economists expect one more trim in 2012. New Zealand is the only country in the survey where economists expect a rate increase in 2012.
AS GOES CHINA
China is the linchpin. If its 2012 growth slows to 8.6 percent, as the consensus forecast predicts, the rest of Asia would feel a modest ripple. If China's growth falls more sharply, Asia could take a direct hit.
A 1 percent decline in China's GDP reduces growth in Singapore, Malaysia and Thailand by 0.7 percentage points, and in Indonesia by 0.3 points, Bank of America-Merrill Lynch economist Hak Bin Chua said.
"The scale of the impact has almost tripled over the past two decades," he said, because China now imports far more than it used to from its Asian neighbors.
"The impact of a China slowdown is still estimated to be less than that of a U.S. slowdown or recession, but the two are converging and are likely to be comparable within the next decade," Chua added.
Compared with the July poll, economists lowered 2012 growth forecasts across the board. Among the sharpest cuts were those for Malaysia and Singapore, two of the countries most closely tied to the global economy.
The forecasts show annual growth rates accelerating in 2012 in Australia, New Zealand, India, South Korea, Thailand and the Philippines. Next year's growth rate will likely trail 2011's in Indonesia, Singapore, China, Hong Kong and Taiwan.
(Editing by Ramya Venugopal)
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Mary Meeker On #OccupyWallStreet: ?People Deserve To Be A Little Angry.?
Source: http://feedproxy.google.com/~r/Techcrunch/~3/qVzLkfg89YM/
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Friday, 21 October 2011
AutoZone to Present at the Upcoming 35th Annual Automotive ...
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Thursday, 20 October 2011
West Japan challenges Tokyo's tasty Michelin crown (Reuters)
TOKYO (Reuters) ? Western Japan challenged Tokyo on Tuesday for its status as the global center of gourmet dining, with the Michelin guide awarding area restaurants more of the coveted three-star ratings than those given to establishments in the capital.
A total of 15 restaurants in the Kansai area, which centers on Japan's second-largest city of Osaka and the ancient capital of Kyoto, were awarded top three-star ratings, three more than last year and one more than Tokyo was given.
Tokyo last year received more Michelin stars than any other city in the world for the fourth year in a row.
Of the restaurants named in the newest edition of the guide to the Kansai region, a popular tourist area known as the heartland of Japanese traditional culture, 12 serve Japanese cuisine and two fusion. The last serves "contemporary French."
New to the guidebook this year were the cities of Kobe and Nara, accounting for three of the three-star establishments. Michelin defines three-star ratings as "exceptional cuisine, worth a journey."
Wa Yamamura, a Japanese restaurant in Nara, leapt to the top of the awards in its first listing.
The restaurants Fujiya 1935 and Koryu in Osaka, whose inhabitants have long been jokingly known in food-obsessed Japan as "those who court financial ruin by extravagance in food," were promoted to three stars from two.
Among the 300 establishments given stars, 61 -- including two traditional inns -- received two stars, while 224 got one.
"Japan is truly a unique country, where many cities have cuisine of a very high quality," said Bernard Delmas, president of Nihon Michelin Tire, in a statement.
"That is why, even in the fifth year of the arrival of our Michelin guide in Japan, we continue to discover new stars to introduce to our readers," he said.
The award is especially respected in Japan, where diners are willing to wait in long lines and pay high prices at noted establishments.
Included in this year's guide for the first time were Korean restaurants.
Kyoto's three-star restaurants, all Japanese, are Chihana, Hyo-tei, Kikunoi Honten, Kitcho Arashiyama Honten, Mizai, Nakamura and Tsuruya. Osaka's three-star Japanese restaurants are Kashiwaya, Koryu and Taian, while Kobe's Japanese winner is Komago.
The fusion restaurants are Ca Sento in Kobe and Fujiya 1935 in Osaka, while the French restaurant is Hajime in Osaka.
The first Michelin restaurant guide, aimed at chauffeurs in the early days of motoring, was published by the tire company in 1900, with the star rating system introduced in the 1920s.
The company only ventured out of Europe for the first time in 2005, with its guide to New York. Its Tokyo guide, launched in late 2007, was its first in Asia, although it has since added Hong Kong and Macau.
(Editing by Paul Tait)
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Romney jabs Cain's '9-9-9' plan (AP)
WASHINGTON ? Hours before Tuesday's night's presidential debate, Mitt Romney is sharpening his criticism of his rival's tax plan.
The former Massachusetts governor says Herman Cain's "9-9-9" tax plan still needs a lot of work. And he says that most middle-income Americans would end up paying more if Cain has his way.
Cain is a former business executive who recently jumped into top-tier status in the Republican presidential primary contest, buoyed in part by his simple tax plan. He's calling for a 9 percent national sales tax and 9 percent tax rates for personal income and corporations.
Romney criticized the plan on a conference call with supporters Tuesday afternoon. He warns that senior citizens and those on fixed incomes in particular could face significantly higher taxes under the 9-9-9 proposal.
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Wednesday, 19 October 2011
China quizzes audit giants on foreign regulator contact (Reuters)
NEW YORK/SINGAPORE (Reuters) ? China's financial regulators have asked the world's biggest audit firms to urgently review their work on U.S.-listed Chinese companies and give details on information they may have provided to overseas regulators, two sources told Reuters.
The unprecedented move, following a string of accounting scandals at U.S.-listed Chinese companies, is set to ratchet up tensions between the financial regulators of America and China.
The request, sources said, is seen as a direct response to the move by the U.S. regulators in the case of scandal-hit Longtop Financial Technologies Ltd, and to ensure that firms do not succumb to pressure to hand over documents to regulators outside of China.
Last month the U.S. Securities and Exchange Commission (SEC) asked an American court to enforce a subpoena it sent to Deloitte Touche Tohmatsu's China practice for documents from its audit of Longtop.
Two sources from the audit industry told Reuters that the Ministry of Finance and China Securities Regulatory Commission (CSRC) met last week with the so-called 'Big Four' audit firms -- KPMG, PricewaterhouseCoopers, Ernst & Young and Deloitte -- along with two smaller firms.
The firms were requested by the government to conduct an urgent review of all audits they had done on U.S.-listed Chinese firms in 2010 along with work on U.S. initial public offerings by Chinese companies.
They have been asked to report back by the end of this week with information on whether audit work papers or other client information were given to overseas regulators or any of their overseas practices.
One source, who can't be named due to the sensitive nature of the meeting, said the Chinese authorities emphasized to the firms their rules on confidentiality.
"We are being asked to give that message to foreign regulators that seek to get information from us," the source said.
The second source said that the information requested included all correspondence on U.S.-audit work between the firms' mainland Chinese offices and their counterparts in Hong Kong and Macau. Firms have also been asked to provide details of audits done by their Hong Kong offices on U.S.-listed Chinese companies, provided their main operations are on the mainland.
"Given what's happened in the States recently with the SEC ratcheting up the pressure, there was likely to be some sort of reaction and this is part of it, if not the total of it," said one industry expert who did not have direct knowledge of the meeting.
CAUGHT IN THE MIDDLE
The request is likely to heap more pressure on auditors caught in the middle of competing demands from the U.S. and Chinese regulators.
"I would guess they (auditors) are terrified," said Paul Gillis, a former partner for PWC and visiting professor of accounting at Peking University. "This is not a pleasant time for them and I think they would like to find a resolution to these problems as quickly as possible."
Gillis added that auditors may well have provided some information to the U.S. SEC in response to questions on listed Chinese companies, while the exchange of information with their overseas offices happens frequently.
"They (Chinese regulators) are going to learn, if the firms are honest about what they are doing, that they have shared a lot of information from China with foreigners," he said.
The CSRC and China's Ministry of Finance ministry had no immediate response when reached by phone. Reuters asked all of the 'Big Four' firms about the meeting. PWC, KPMG and Ernst & Young declined to comment while Deloitte did not immediately respond.
Gillis said it was unlikely the big audit firms will face major sanctions for disclosing that they passed on information to their overseas offices or foreign regulators but will likely be told such behavior will not be tolerated in future.
U.S. accountancy watchdog Public Company Accounting Oversight Board (PCAOB) has been negotiating with the Chinese authorities to be allowed to conduct inspections of mainland firms that audit Chinese companies listed in America.
However, the momentum of the talks appears to have been slowing in recent weeks, with no date yet set for the next round of discussions.
Earlier this month the PCAOB's chair James Doty said he could not wait indefinitely for an agreement and indicated they may consider taking alternative measures against audit firms that would not co-operate with inspectors.
(Additional reporting by Nanette Byrnes in NEW YORK and Don Durfee in BEIJING; Editing by Muralikumar Anantharaman)
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Michael Jackson doctor's trial to resume Wednesday (AP)
LOS ANGELES ? A judge says the involuntary manslaughter trial of Michael Jackson's doctor will resume Wednesday and defense attorneys will begin their case on Friday.
The judge said Tuesday that if the prosecution's final witness finishes his testimony Wednesday, there will be no testimony on Thursday. Defense attorneys for Dr. Conrad Murray say their witnesses aren't available until Friday.
The defense plans to call 15 witnesses, including the head of AEG Live, the company that promoted Jackson's planned series of comeback concerts. Other witnesses will include police detectives who have not testified, character witnesses and experts.
Jurors haven't heard any testimony since Thursday due to the schedule of a witness and to give defense attorneys time to investigate newly conducted tests to determine how much of the sedative lorazepam was in Jackson's body.
Murray has pleaded not guilty
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Tuesday, 18 October 2011
Justin Bieber Caught 'Christmas Spirit' In 'Mistletoe' Video
'Mistletoe' video premieres tomorrow at 7:54 p.m. ET/PT on MTV, with in-depth live stream to follow on MTV.com.
By James Montgomery
SANTIAGO, Chile — Justin Bieber faced plenty of challenges when he shot his "Mistletoe" video, the least of which was the fact that he did it in September, in Tennessee, with fake snow cascading down from the sky. The way he tells it, the biggest obstacle was not even being weirded out by Santa.
"It was different because, like, it's a Christmas video, so you gotta get your Christmas spirit on," Bieber told MTV News backstage in Santiago, Chile, where he played to 55,000 screaming fans on Saturday. "We had Santa there. He was kind of interesting because he had this finger that would light up, but I never knew that, so he would come up to me randomly and pointed at me and his finger lit up and it was really strange. I was like, 'Santa doesn't do that, my friend.' "
Of course, Bieber was quick to add that despite the awkward interaction, he remains decidedly pro-Santa, since "he gets kids in the holiday spirit."
Bieber's "Mistletoe" video will make its world premiere Tuesday at 7:54 p.m. on MTV — with a special live stream to follow on MTV.com, where we'll roll out more of our interview with him! — and on Monday (October 17), he released the song to iTunes. He's rather proud of how both turned out, because he got to collaborate with two of his favorites: director Roman White and the production team known as the Messengers.
"[Roman] can tell a story really well, so we wanted to use him," Bieber explained. "He shot the 'One Less Lonely Girl' video, and I thought he did a great job; he shot the 'You Belong [With] Me' video with Taylor Swift, and he had a lot of great experience and a lot of great work.
"[And] Nasri [one member of the Messengers team], he's really intelligent, he can tell a story as well, Christmas, anything," he continued. "So we were thinking of doing a Christmas album last year, we never really got to it. And this year I was like, 'This year I really want to do it,' so we collaborated on some ideas and sure enough, we got some great Christmas music. ... I think I have a few classics on the album, I really, really do. I think that there's some songs on there that are so catchy and everyone's going to want to sing them every Christmas."
Catch the premiere of Justin Bieber's "Mistletoe" video Tuesday, October 18, at 7:54 p.m. on MTV, with a full interview to follow on MTV.com.
Source: http://www.mtv.com/news/articles/1672652/justin-bieber-mistletoe-christmas-spirit.jhtml
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Monday, 17 October 2011
Saturday Night Live Lines Up November Hosts, Musical Acts
It will be a November to remember on Saturday Night Live, that appears certain.

The iconic sketch comedy program will be on hiatus until the fifth of next month, but NBC announced its upcoming hosts/musical acts today as follows:
- November 5: Charlie Day/Maroon 5
- November 12: Emma Stone/Coldplay
- November 19: Jason Segal/Florence + the Machine
Source: http://www.thehollywoodgossip.com/2011/10/saturday-night-live-lines-up-november-hosts-musical-acts/
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Passenger charged with striking flight attendant
By Pete Williams, NBC News
In what investigators say is another episode of a drunk and unruly airline passenger, an American Airlines direct flight from New York to Los Angeles landed last night in Denver after a man became unruly and hit a flight attendant. This time, the government is filing serious charges.
Federal prosecutors offer the following account of what happened.
They say the passenger, Varoujan Khodjamirian, had several drinks and became loud and disruptive about 90 minutes into Flight 21, a Boeing 767-200 with about 160 passengers onboard. When those sitting near him complained, they were re-seated, but he started kicking the seats in front of him.
When flight attendants were unable to quiet him down, they moved him to the last row of seats, but he continued to be loud and hit one of them in the face. He also yelled, "I kill you children. I kill your mother. I will beat you all down and kill you," along with several obscenities. Flight attendants handcuffed him with plastic restraints, and two of them actually sat on him until the plane landed in Denver, where Khodjamirian was arrested.
He's been charged with interfering with flight crew members and attendants, a crime which provides a maximum penalty of 20 years in prison and a fine of up to $250,000.
Khodjamirian lives in Long Island, N.Y., and is of Armenian descent. He has requested a Russian interpreter.
More on Overhead Bin
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Sunday, 16 October 2011
Pope wheeled up St Peter's instead of walking (Reuters)
VATICAN CITY (Reuters) ? Pope Benedict was wheeled up the main aisle of St Peter's Basilica on a mobile platform at a ceremony on Sunday to spare him the unnecessary fatigue of walking, but the Vatican said there was no concern for his overall health.
The 84-year-old pontiff stood on the platform as aides pushed it up the central aisle, which is about 100 meters (yards) long.
Wearing green vestments, he blessed the faithful and then celebrated Mass from the main altar. He appeared to be in good health. He later used the same mobile platform to leave the basilica.
"This is just not to tire him," chief Vatican spokesman Father Federico Lombardi said. "Nothing else should be read into the general state of his health, which is good."
The platform, which has three steps and brass handles, was built to transport the late Pope John Paul during the last five years of his life.
John Paul, however, had suffered a broken femur and had undergone hip replacement surgery, an operation that left him with a permanent limp and other walking difficulties.
Benedict, who was elected in 2005 after John Paul's death, has appeared to be in generally good health, though Vatican sources say he suffers from high blood pressure.
Benedict's schedule of public and private engagements has been far less hectic than that of his predecessor.
Aides say that because he was already 78 when he was elected, unlike John Paul who was 58, Benedict decided to pace himself more carefully and limit his activities.
During the mass on Sunday, the pope announced that he was calling a "Year of Faith" for the entire 1.2 billion-member Roman Catholic Church that would start on October 11, 2012.
He said he hoped the event would be an opportunity for all Catholics to "strengthen our faith in God," and that he would soon publish an "apostolic letter" outlining what he wants the Church to gain from the year of reflection.
Benedict has started a new Vatican office, the Pontifical Council for the Promotion of New Evangelisation, to shore up and spread the faith in economically advanced regions such as Europe and the United States, where the Vatican believes it has been weakened by secularism.
(Reporting By Philip Pullella; Editing by Tim Pearce)
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Saturday, 15 October 2011
Practices get under way for men's basketball (AP)
Things were pretty normal for the opening night of practice for Division I men's basketball.
Most of Friday night's events were called some form of madness, from Big Blue to Mountaineer to First Night. Most of them ended well before the midnight part of many of their names.
There were also some coaches who let the fans know things were going to be serious this season.
Connecticut coach Jim Calhoun didn't promise a repeat of last season's national championship ? the Huskies' third in a span of 13 years ? but he didn't discourage any thoughts of it.
Calhoun said he believes his team may be more talented than the one that beat Butler in April.
Kentucky made it to the Final Four as well last season, but the Wildcats lost to Connecticut in the semifinals.
Coach John Calipari made it clear what this season's goal is by saying it's time to turn the page from anticipation to preparation.
"Tonight we begin to write the next chapter," Calipari said. "Tonight we feel the Kentucky effect in full force as we once again redefine college basketball. ... We see no plateaus. We see no stopping points. Let's persist beyond what it is, and let's try to create what was never before imagined. We do more than move the needle. We are the needle. We are UK."
Vanderbilt isn't usually mentioned as a national contender. But the Commodores have all five starters back this year.
"More than ever before we are going to be the hunted rather than the hunter," coach Kevin Stallings said. "We expect to get everyone's best shot. We look forward to getting everyone's best shot. We are excited about perhaps being a program that can have that said about them. Quite honestly, we have never been that program before. That has always been Kentucky or Florida or somebody else in the (Southeastern Conference). Maybe, we have a chance to be that program now."
Stallings sent the crowd of 3,500 at Memorial Gymnasium into pandemonium when he made a half-court shot from behind his back ? on the first try.
Some of the highlights of the start of practice:
_This was the seventh time Big Blue Madness was held at Rupp Arena, and Kentucky opened the doors at 6 p.m. with fans filling 20,000-plus seats quickly. Students in the section behind one basket held up a very large banner reading "KENTUCKY BASKETBALL NEVER STOPS" before the festivities started.
Kentucky kicked it off with a video highlighting the hundreds of students who camped out in tents for tickets to attend Big Blue Madness. As freshman Anthony Davis said in the video, "They just want to see us win a championship this year."
The Wildcats came down white staircases bookending a large video screen on the stage at one end of Rupp, and the fans stayed on their feet.
_Connecticut's teams showed off their skills in front of their fans for the first time since the men brought home the program's third national championship and the women returned from their 12th Final Four.
They showed off their athleticism for more than 10,000 fans who came out to watch the school's annual "First Night" show.
Freshman guard Ryan Boatright, generously listed in the media guide at 6-feet-0, won the dunk contest. Niels Giffey topped freshman Kaleena Mosqueda-Lewis from the women's team in the 3-point contest, and there was dancing and contests for students, even appearances from alumni such as Ray Allen and the hero of last year's national title run, Kemba Walker.
_Vanderbilt hosted its first Midnight Madness session in six years. Vanderbilt went 23-11 last season but failed to get out of the first round of the NCAA tournament for the second straight year. Each of the starters and the top three reserves return. Among those coming back are John Jenkins, Jeffery Taylor and Festus Ezeli ? all three passed on entering the NBA draft last spring.
_Butler stuck to its traditional opening-night schedule. Coach Brad Stevens closed practice, ditched the dunk contests and got down to coaching basketball earlier than most other teams.
Just 15 minutes after the official start to basketball season, the two-time national runners-up hit the court at Hinkle Fieldhouse without a fan in sight.
The Bulldogs never celebrated Midnight Madness when it was covered live on late-night television, and still don't open it up for fans even though the NCAA has agreed to let teams start working out earlier in the day.
_New Arkansas coach Mike Anderson received the loudest ovation inside Bud Walton Arena. He walked back onto the court he called home as an assistant coach for 17 seasons under former coach Nolan Richardson. Anderson was greeted with plenty of support from the estimated 5,000 who attended "Primetime at the Palace."
_North Carolina kicked off a season of high expectations in front of a packed arena of about 21,000 fans. The Tar Heels held their annual "Late Night with Roy" preseason event in the Smith Center, which included an intrasquad scrimmage as well as the players performing dances and skits in a night of fun before things get serious for a team expected to contend for the national championship.
All five starters are back from a team that won the Atlantic Coast Conference regular-season title and got within a game of the Final Four.
_Memphis unveiled its team before an almost full house at the FedExForum.
Fans were waiting outside the arena when the doors opened 90 minutes before the start of Memphis Madness. The festivities included a dunk contest, a 3-point shooting display and a scrimmage.
Rapper Rick Ross was supposed to be the featured entertainment for the evening, but he had a medical problem on a flight from Fort Lauderdale, Fla., to Memphis, that forced him to miss the event.
_West Virginia's Mountaineer Madness had a season-opening scrimmage, slam-dunk contest and a special musical performance.
Deniz Kilicli, a native of Istanbul, Turkey, and an amateur guitarist who has performed around town, entertained the crowd by performing the university's adopted fight song, "Country Roads," with his teammates. He played electric guitar as the gold-and-blue clad Mountaineers joined the throng in John Denver's song.
_Duke opened practice with its "Countdown to Craziness," and one of the highlights was the intrasquad scrimmage that was the debut for freshmen Austin Rivers, Quinn Cook and Marshall Plumlee in front of the Cameron Crazies.
_The Syracuse team was already on the court when Orange coach Jim Boeheim gave the crowd of 20,000 in the Carrier Dome some great news.
He stepped to the center of the court bearing his name and declared "There's one more guy here." He pointed to the tunnel at the corner of the building and yelled the name they all were hoping to hear.
New York Knicks forward Carmelo Anthony jogged onto the court where he left his definitive mark during Syracuse's 2003 national championship season. It was all part of Syracuse's annual Midnight Madness.
_Hours after letting Kansas fans hear some bad news about the program, Jayhawks coach Bill Self made a lot of them smile.
On Friday afternoon, Self announced that the NCAA ruled freshmen Ben McLemore and Jamari Traylor partial qualifiers and they won't eligible to play this season.
On Friday night, Self rode to the center of James Naismith Court on a specially made Kansas motorcycle to commemorate the 2008 national championship. He was even wearing a black leather jacket and black leather chaps. It wasn't his idea to wear the chaps.
"They told me I need to look like a biker for whatever reason," Self said. "I tried to do what they ask me to do."
McLemore and Traylor will be able to practice starting Dec. 16, and will be eligible for competition for the 2012-13 season. They can work out and lift on their own.
_Maryland Madness had several members of the 2002 national championship team, along with former head coach Gary Williams, on hand to mark the 40th anniversary of the first Midnight Madness. Steve Blake, Byron Mouton, Chris Wilcox and Mike Grinnon, along with current NBA star Greivis Vasquez and former NBA standout Steve Francis, participated in a star-studded alumni game.
This version of Maryland Madness had a different feel than the ones that preceded it. The first one, held in 1971 under coach Lefty Driesell, was little more than a one-mile run around the track at midnight by the players on the first official day of practice.
In recent years, the event revolved around Williams, the winningest coach in school history.
_St. John's coach Steve Lavin wasn't able to attend the school's tipoff event. He did send a message to the fans.
"Last week's surgery was a success. Now my return to coaching duties will be dictated by the healing process," Lavin said in a statement Friday night. "I'm under the expert care of Dr. Scardino at the Memorial Sloan-Kettering Cancer Center and we are working closely to measure the daily progress being made during this vital recovery period."
Lavin is recuperating from prostate cancer surgery on Oct. 6.
"Naturally, I wish I was at Carnesecca Arena tonight to participate in the tip-off festivities with our team, and celebrate the start of the college basketball season with our loyal fans!" Lavin said.
_Arizona coach Sean Miller isn't a big proponent of celebrating the start of practice.
"Our red-blue game really has become midnight madness. Your midnight madness is just a show because at this point your guys don't know enough of what you do to even play. They're almost playing a glorified pickup game," he said. "I think it means more to them and all the things that happen in a midnight madness happen in the afternoon, at a sane time so if you want to go to bed at 10:00, you can. You don't have to be in McKale at 1:30 or 2 in the morning and then have to get back up as a college coach or player the next day. To me, it makes a lot more sense across the board."
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Bose's OE2 and OE2i on-ear headphones pack brand recognition, little else
Continue reading Bose's OE2 and OE2i on-ear headphones pack brand recognition, little else
Bose's OE2 and OE2i on-ear headphones pack brand recognition, little else originally appeared on Engadget on Thu, 13 Oct 2011 08:10:00 EDT. Please see our terms for use of feeds.
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Friday, 14 October 2011
Bus 290 ( Business Ethics ) | Written Essays
Statistics of the whole essay
Quote from this essay
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The programs aimed at diversifying the company will remain a tool of the powerful and nothing will really ever change The 35 million Texaco set aside for its diversity program would not be well spent in the expansion of such programs , as CEO Peter Bijour claims
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A corporation should not be given the same rights as citizens there should be no privacy in the decisions made at the top The 35 million should be in some small way used as early retirement packages for corrupt executives so the company can begin again as a model of diversification
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When this is the case , and it becomes fashionable to implement policies and programs which aim at highlighting diversity and protecting women and minorities , the good old boy ?s will only do the bare minimum in achieving the supposed goals of the policies and programs
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Usually , and especially in the case of Texaco this only means claiming you have such programs but not actively working towards the positive solutions at which the programs aim
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Paper Topic: Bus 290 ( Business Ethics ) As the article stated , Texaco , along with the other petroleum companies had yet to rid themselves of the good old boy ? culture that dominated , preventing the advancement of women and minorities to positions of more power
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When changes are implemented in the middle or bottom of the hierarchy , nothing changes at the top
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Rather , the money should be used to make the company much more transparent
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When the problem rests at the top of the hierarchy , the only way change will occur is if something is done about those at the top
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Source: http://www.writtenessays.net/bus-290-business-ethics-13/
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Thursday, 13 October 2011
List Building Systems - Affiliate Website Marketing
Wednesday, October 12th, 2011 at ?

If? you are an online marketer, the first thing you need to focus on is what kinds of list building systems you are going to utilize in your efforts to reach the highest number possible of your potential customers. Having a list of prospects is going to make all the difference in the world when it comes to how profitable you can build your online business. When you have the proper list building systems ready to go to work for you, getting laser targeted traffic for your products and services becomes as easy as the? push of a button. Yes really, your marketing practically becomes an automated process.
The more I promote my business on the Internet, the more I realize how important it is to have a system that can develop a list of potential customers who are always on hand when you need to market your primary business. Trying to market your primary business first hand can be difficult because most likely that the cost to enter will be quite high and the work involved can be overwhelming for many people. There are a list building system can be beneficial to you.
What is a list building system? This is a system where the cost is little or nothing to attend, give value to the prospect and is easy to learn for beginning network marketer. By advertising this system using a splash page or capture page and an opt-in form so the person can get more information about your product, you have now caught the prospect?s name can be added to your list. The prospectus will now get information about the product you offer, and as long as it is of great value to the product and the price is either free or very cheap, you will begin to develop trust with the prospect that will enable you to view your primary business to him when the time is right.
There are many of these lists to build systems out there today. I use one that can be done entirely via e-mail with no phone jack is needed, is free to join and can develop into a primary business if you want to invest any money. Most of the Internet ?will have-a-ha?s? do not want to talk on the phone. They are either too shy or have little confidence in their abilities because they are new to the company and are afraid of making a mistake. By hiding behind his computer, so to speak, the individual can continue to work their business, learn about internet marketing and be secure in their marketing skills. When they do become more comfortable, so they can be ready to tackle my primary business that does not require any interaction on the phone.
Be extremely careful when you choose your list building system (or any company for that matter). The first thingI do is email the company and wait for a response. If they take more than 24 hours to get back to me, I do not bother with them. The best companies get back to you within a day or less. I also look for an answer that is not only fast but friendly and supportive. If I have to deal with someone who is not on my side, there is no point in working with them. Another thing I look for is a valid business address and phone number. If the company does not list their phone and address that does not necessarily mean that they are not reputable but it helps with their credibility.
Take the time to find and inexpensive or free service that you can develop that list building business. Taking this route to build your list is highly recommended as the best way to get the list started and to get trust and respect from your prospects so ultimately you can offer your primary business where money is waiting.
Website: http://www.beginyourfuture.com
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- Review of Sprout Builder When Sprout Builder was first released in beta, this drag and drop Flash authoring widget building environment was immediately on fire. Although there was not much wrong with the original Sprout Builder, they have recently released a much more sophisticated version of their flash building services today. The new Software......
Tagged with: Automated Process ? E Mail ? marketing ? money ? Network Marketer ? Prospects ? Prospectus ? targeted traffic
Filed under: List Building
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Source: http://kimaron.com/list-building-systems
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